Scientists theorize that the combination of Bactrim and alcohol leads to an inhibition of acetaldehyde dehydrogenase which is how alcohol is converted into acetic acid in the liver. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If acetaldehyde dehydrogenase is less active, alcohol toxicity can build up and can cause what is known as a disulfiram reaction . Helpful, understanding insights from Doctors: Worried about negative side-effects? However, alcohol is a common part of social lives. This reaction is similar to the reaction caused by the drug disulfiram, sold as Antabuse, a drug to deter alcoholics from drinking. However, alcohol does not reduce the efficacy of Bactrim which is why there is no need to worry about the treatment unless the dose is vomited out. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. This is especially true if the alcoholic is still drinking. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Alcohol can interact with many types of medication, including antibiotics like Bactrim.
Mixing alcohol and Bactrim is not entirely safe. Check your food and medicine labels to be sure these products do not contain alcohol. This reaction is characterized by: Do not drink alcohol while you are taking trimethoprim. If you are an alcoholic or don’t have control over drinking, it’s better to talk to your doctor and substitute Bactrim with some other medicine. Alcohol doesn't lower the ... (Tindamax), and sulfamethoxazole and trimethoprim (Bactrim) — should not be mixed with alcohol because this may result in a more severe reaction. Alcoholics should use Bactrim with caution and only under the care of a doctor.
Alcohol With Bactrim. Ask your doctor before using trimethoprim together with ethanol. A general rule to follow is that if you are sick enough to require antibiotics, you should not be drinking alcohol. Bactrim may interfere with acetaldehyde dehydrogenase, a substance that helps break down alcohol so your body can metabolize it. Dr. Fowler answers whether or not you can drink alcohol while taking Bactrim. In regards to Bactrim with alcohol specifically, Bactrim can inhibit acetaldehyde dehydrogenase, which is largely responsible for alcohol metabolism .
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