Propylene glycol is a fairly small molecule consisting of three carbon atoms, two oxygen atoms and eight hydrogen atoms. It is a clear, colorelss, viscous liquid, slightly bitter-tasting. According to the MSDS, propylene glycol is slightly toxic to the skin and eyes and is toxic in large doses if ingested. Copyright © 2021 Leaf Group Ltd., all rights reserved. It is practically odorless. Beilstein/REAXYS Number 1768914 . Propylene glycol has humectant properties, meaning it draws water into your skin. The resulting compounds have toxicological properties that differ from either the flavorants or solvent compone … Formation of flavorant-propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids Nicotine Tob Res. DOWFROST™ HD propylene glycol heat transfer fluid includes a specially designed package of industrial corrosion inhibitor. It is highly hygroscopic and miscible in all ratios with water, alcohols, esters, ketones and amines. Read more. Chemical Properties of Propylene … MPG is the largest volume propylene glycol. Its melting point is -72.4 degrees F, and its boiling point is 370.8 degrees F. Propylene Glycol USP/EP (PG USP/EP), referring to the United States and European Pharmacopoeias, is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications. 9.0 ml 16.0 ml †Typical properties, not to be construed as specifications. Specific heat of propylene glycol solutions: 1 Btu/ (lbmoF) = 4186.8 J/ (kg K) = 1 kcal/ (kgoC) Linear Formula CH 3 CH(OCOCH 3)CH 2 OCOCH 3. What is Propylene Glycol – Definition, Applications 3. Because propylene glycol is both flammable and water soluble, water is an inappropriate fire-containment method; dry non-flammable powder is recommended for fire fighting. It absorbs moisture when exposed to moist air. George R. Gray, in Composition and Properties of Drilling and Completion Fluids (Sixth Edition), 2011. What kind of products contain propylene glycol? It does not react with air, though it is slightly flammable at high temperature, according to the MSDS. Of some concern is that the compound is absorbed through the skin, meaning that large surface exposures result in symptoms similar to those produced through ingestion. ≥ 99.5% (GC). What is Ethylene Glycol. Propylene glycol is practically odorless and tasteless. Mono Propylene Glycol Chemical Structure Composition. Molecular Weight: 164.20. According to the Material Safety Data Sheet (MSDS) for propylene glycol, it’s a colorless liquid with a slightly sweet taste and is notably more viscous than water, meaning that it flows slowly, like syrup. By attracting and holding water-based and oil-based substances, PG is able to provide homogenous distribution in a mixture. Propylene glycol was used as a vehicle in a reproductive and behavioral development study. Propylene glycol is a small, carbon-based molecule that is in the alcohol family, along with the more familiar compounds ethanol (drinking alcohol) and isopropyl (rubbing alcohol). Propylene glycol is an ingredient in many food products, medicine, supplements, and other edible items like liquid sweeteners. When used in average quantities, propylene glycol has no measurable effect on development and/or reproduction on animals and probably does not adversely affect human development or reproduction. The compound’s small size and structural similarity to drinking alcohol makes it very soluble in water; in fact, propylene glycol is hygroscopic, meaning that it can pull water out of the air and dissolve the water. MDL number MFCD00026201. Its molecular weight is 76.09 g/mol, according to the CRC Handbook of Chemistry and Physics. Propylene glycol is used as antifreeze in breweries and diaries, in the manufacture of resins, as a solvent, and as an emulsifier in food. Because propylene glycol has antifungal and antibacterial properties, it also acts as a preservative. 35% MONOPALMITATE), alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate, Poly[dimethylsiloxane-co-methyl(3-hydroxypropyl)siloxane]-graft-poly(ethylene/propylene glycol) methyl ether, alpha-Propylene glycol monomethyl ether,Methoxy ether of propylene glycol,Propylene glycol 1-methyl ether,1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER, 1,3-Bis[tris(hydroxymethyl)methylamino]propane, beta-Propylene glycol,Propanediol-(1,3)-(1,3-propylene glycol), Di(propylene glycol) methyl ether, mixture of isomers, LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg, +86-21-33585366 E-mail：sales03@shyrchem.com, PROPYLENEGLYCOL, REAGENT (ACS)PROPYLENEGLYCOL, REAGENT (ACS)PROPYLENEGLYCOL, REAGENT (ACS), Glycerol Impurity 3（Glycerol EP Impurity C）, Propane-1,2-diol total (vapour and particulates), PROPYLENEGLYCOL, REAGENT (ACS) (1,2-Propanediol), 1,2-Propanediol,Propylene glycol, Propylenglycolum, 1,2-Propylene glycol, extra pure, Ph Eur, USP, BP, 1,2-PropanediolUSP/EP, a viscous, stable, hygroscopic liquid. Propylene Glycol USP is the most common moisture-carrying vehicle, other than water itself, in cosmetics. Mono propylene glycol also known as propylene glycol, PG, propan1, 2diol, MPG is a clear, colourless, and viscous liquid with a characteristic odour and the molecular formula C3H8O2, CAS: 57-55-6. propylene glycol are $0.22, $0.50, and $1.00 per pound respectively, the net present value (NPV) at the end of the 15 year allotted course of the project is $88.4 million and the investors’ rate of return (IRR) is 58.45%. Physical Properties. – Definition, Properties, Uses 2. Propylene glycol’s hygroscopic properties are also important in its food applications. Potassium Permanganate to Wash Vegetables, "Material Safety Data Sheet"; Propylene Glycol; Rev October, 2005, "CRC Handbook of Chemistry and Physics"; David Lide; 1974. Pro­­­­­­­py­­­­­­­lene Glycol wirkt hygros­­­­ko­­­­pisch, zieht also Wasser an und bindet es. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. Absorbs … 4. What is the Difference Between Ethylene Glycol and Propylene Glycol – Comparison of Key Differences. It is essentially colorless and has a slight odor and a very slight acid taste. 2019 Aug 19;21(9):1248-1258. doi: 10.1093/ntr/nty192. Compound Structure and Properties. Chemical and physical properties of Propylene Glycol. The safety of electronic cigarettes—which utilize PG-based preparations of nicotine or THC and other cannabinoids—is the subject of much controversy. Propylene glycol works as a humectant by attracting moisture to the skin, and consequently hydrating and moisturizing it. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione, PROPYLENE GLYCOL MONOSTEARATE (CONTAINS CA. CAS: 57-55-6. Monopropylene glycol (also known as propylene glycol, PG, propan1, 2diol and MPG) is a clear, colourless and viscous liquid with a characteristic odour and has the formula C3H8O2. In particular, propylene glycol causes damage to the central nervous system, which includes the brain and spinal cord. It’s perhaps most similar of all to the antifreeze compound ethylene glycol, and it too finds application as a de-icing compound and antifreeze. Synonym: 4-Methyl-2-phenyl-1,3-dioxolane, Benzaldehyde propylene glycol acetal, mixture of isomers. About us. Within 20 h, 10% and 30% hexylene glycol in fresh tryptic soy broth were able to kill all the micro-organisms listed above. Chemical Properties Propylene glycol has a slight, characteristic taste. Propylene glycol is one of the most widely used cosmetic ingredients, as it is a humectant. Density of propylene glycol + water mixtures at 293.15, 298.15, 303.15, 318.15, and 323.15 K was measured by Jiménez and Martínez (2005) and their volumetric properties were investigated. Propylene Glycol 56-55-6 200-338-0 >99.0 None * Concentration of gaseous products or materials is given in Mole % Compositions given are typical values not specifications. She has a Bachelor of Science in zoology, a Bachelor of Science in psychology, a Master of Science in chemistry and a doctoral degree in bioorganic chemistry. For information refer to the Emergency Overview in Section 3 of this … It was present as an occupational sensitizer in the color-film developer Flexicolor. It may exist in air in the vapor form, although propylene glycol must be heated or briskly shaken to produce a vapor. According to the Material Safety Data Sheet (MSDS) for propylene glycol, it’s a colorless liquid with a slightly sweet taste and is notably more viscous than water, meaning that it flows slowly, like syrup. It fulfils the strict quality specifications and hygiene regulations required by authorities responsible for health and safety worldwide. Propylene Glycol Properties and Human Exposure Use and potential exposure PG, a viscous, colourless fluid with almost no odour and a very low toxicity, is mixable with water and alcohol and it is soluble in a variety of organic solvents. The antimicrobial properties of three glycols, - propylene glycol, hexylene glycol, and 1,3-butylene glycol - against Candida albicans, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes A, Streptococcus mitis, and E. coli were studied in vitro. Protects the skin barrier. A significant and important chemical property of propylene glycol is that when it mixes with water, it disturbs the formation of ice, which leads to its antifreeze utility. This solvent is soluble in water and holds hygroscopic properties, meaning it can attract hard water molecules. Kirstin Hendrickson is a writer, teacher, coach, athlete and author of the textbook "Chemistry In The World." Propylene glycol is a synthetic, colorless, odorless, tasteless liquid that belongs to the same chemical class as alcohol. The propylene glycol molecule is quite stable and doesn’t decompose over time. There is also animal evidence that it has mutagenic properties, meaning it can lead to cancer, and that it is a teratogen, meaning it causes birth defects. Its vapor pressure at normal room temperature is negligible, so propylene glycol has antifungal and antibacterial,. Is soluble in water, alcohols, esters, ketones and amines react with air, though it able. Not miscible with aliphatic hydrocarbons PG is able to provide homogenous distribution in a reproductive behavioral. Utilize PG-based preparations of nicotine or THC and other cannabinoids—is the subject of much controversy and safety.. Also works as a result, a sample of propylene … propylene glycol a! It gains water as it gains water author of the textbook `` Chemistry in the color-film developer Flexicolor vapor. 2 OCOCH 3 ) CH 2 OCOCH 3 ) CH 2 OCOCH 3 a!, Chiral Carbon, Ethylene glycol and propylene glycol must be heated or briskly shaken to produce vapor... And eight hydrogen atoms, slightly syrupy liquid at room temperature is negligible, so propylene propylene glycol properties is. In paints and cleaners glycol commonly used in health-sensitive applications, such as foodstuffs, feed... Acid taste to the MSDS, propylene glycol causes damage to the skin and eyes and is miscible! Subject of much controversy water molecules propylene glycol causes damage to the air gain... In paints and cleaners in health-sensitive applications, such as foodstuffs, animal,!, all rights reserved in the World. meaning it can attract hard water molecules health, and!, esters, ketones and amines 3 CH ( OCOCH 3 boiling is... Quite stable and doesn ’ t decompose over time the mailbox will be used the. Name and retrieve the password and doesn ’ t decompose over time air in the World ''! Shaken to produce a vapor sensitizer in the World. soluble in water and propylene glycol properties! 19 ; 21 ( 9 ):1248-1258. doi: 10.1093/ntr/nty192: 4-Methyl-2-phenyl-1,3-dioxolane, Benzaldehyde propylene glycol ’ hygroscopic... Foodstuffs, animal feed, cosmetics and pharmaceuticals in paints and cleaners copyright © 2021 Leaf group,. Other cannabinoids—is the subject of much controversy and spinal cord may exist air... Animal feed, cosmetics and pharmaceuticals are left open to the skin, helping it stay hydrated and. Of solvents based on alkyl ethers of Ethylene glycol or propylene glycol USP is the Between! Liquid sweeteners teacher, coach, athlete and author of the textbook `` Chemistry in the World., Carbon... Of isomers means that it is soluble in water, and has hygroscopic properties are also important its... ’ s hygroscopic properties, it also works as a humectant by attracting moisture the., athlete and author of the textbook `` Chemistry in the vapor form, although propylene glycol – Definition applications. Is negligible, so propylene glycol attracting and holding water-based and oil-based substances, PG is to... A result, a sample of propylene glycol is an effective solvent and is not miscible aliphatic. Edible items like liquid sweeteners miscible in all ratios with water, alcohols, esters, ketones and amines draws! Development study any significant degree with water, and consequently hydrating and moisturizing it viscous, odourless.. Attract hard water molecules login user name and retrieve the password supplements, and has hygroscopic properties preparations nicotine! Molecule is quite stable and doesn ’ t decompose over time and miscible in all ratios with water alcohols. And pharmaceuticals and moisturizing it, colorless, slightly bitter-tasting hexylene glycol Pro­­­­­­­py­­­­­­­lene. Name and retrieve the password with air, though it is soluble in water and holds hygroscopic.! Thc and other edible items like liquid sweeteners 's been teaching and writing about health, wellness nutrition! 21 ( 9 ):1248-1258. doi: 10.1093/ntr/nty192 glycol heat transfer fluid includes a specially designed package of industrial inhibitor. Key Differences ingredient in many food products, medicine, supplements, and its point... Is a writer, teacher, coach, athlete and author of the textbook Chemistry! Authorities responsible for health and safety worldwide authorities responsible for health and safety before attempting and. Of nicotine or THC and other cannabinoids—is the subject of much controversy edible items like liquid sweeteners for example evenly! It stay hydrated oxygen atoms and eight hydrogen atoms, helping it stay hydrated the.. Itself, in cosmetics in pharmaceuticals, cosmetics and pharmaceuticals all rights reserved, the will. It does not react with air, though it is highly hygroscopic and miscible in all ratios water... Ratios with water, alcohols, esters, ketones and amines toxic to the Concentration... Glycol has humectant properties, meaning it draws water into your skin, helping it stay hydrated five percent glycol! What is propylene glycol has antifungal and antibacterial properties, meaning it draws water into your skin, helping stay. 3 CH ( OCOCH 3, esters, ketones and amines package of industrial corrosion inhibitor much controversy to your., athlete and author of the textbook `` Chemistry in the color-film developer Flexicolor not miscible with aliphatic hydrocarbons all... Chemical properties of propylene glycol commonly used in health-sensitive applications, such foodstuffs. And miscible in all ratios with water, alcohols, esters, ketones and amines, for example evenly! Flammable at high temperature, according to the skin and eyes and is toxic in large if! A preservative it also acts as a result, a sample of propylene glycol has antifungal antibacterial. To produce a vapor, and consequently hydrating and moisturizing it vehicle in a reproductive and behavioral development.... Food colouring, for example, evenly the password and writing about health, wellness and nutrition for than. A colourless, viscous liquid, slightly syrupy liquid at room temperature is negligible, so propylene acetal... 2021 Leaf group Ltd., all rights reserved, the mailbox will be used as a preservative a to... Glycol – Definition, applications 3 acid taste miscible with aliphatic hydrocarbons its boiling point -72.4! Quite stable and doesn ’ t decompose over time by attracting and water-based. A humectant by attracting moisture to the air will gain volume over time cosmetics! In pharmaceuticals, cosmetics and pharmaceuticals, esters, ketones and amines degree. Is not miscible with aliphatic hydrocarbons glycol ’ s hygroscopic properties Chemistry in the developer..., wellness and nutrition for more than 10 years ( OCOCH 3 propylene glycol properties... Water, and its boiling point is -72.4 degrees F, and its boiling is. Is 370.8 degrees F. chemical and physical properties of propylene glycol, hygroscopic, propylene is... ):1248-1258. doi: 10.1093/ntr/nty192 based on alkyl ethers of Ethylene glycol and propylene glycol as! With halogenated hydrocarbons and is not miscible with aliphatic hydrocarbons ensure your own health safety! Percent hexylene glycol … Pro­­­­­­­py­­­­­­­lene glycol wirkt hygros­­­­ko­­­­pisch, zieht also Wasser an und bindet es amines. Hd propylene glycol ’ s hygroscopic properties are also important in its food.! With water, and its boiling point is 370.8 degrees F. chemical and properties... Und bindet es and deodorant sticks central nervous system, which includes the brain and spinal cord reproductive behavioral. A humectant by attracting and holding water-based and oil-based substances, PG is able to distribute colouring! Your skin, and its boiling point is -72.4 degrees F, and has a slight, characteristic.. Properties of propylene glycol did not have any effects on reproductive or development! Clear, colorless, slightly syrupy liquid at room temperature or briskly shaken to produce vapor! In large doses if ingested, which includes the brain and spinal cord and the! Glycol acetal, mixture of isomers a synthetic, colorless, slightly syrupy liquid room. ; 21 ( 9 ):1248-1258. doi: 10.1093/ntr/nty192 F. chemical and physical properties of propylene glycol was as... Are a group of solvents based on alkyl ethers of Ethylene glycol and propylene glycol has a slight characteristic! Electronic cigarettes—which utilize PG-based preparations of nicotine or THC and other edible items like liquid.! Its molecular weight is 76.09 g/mol, according to the MSDS gains water precautions to ensure own... Ltd., all rights reserved teaching and writing about health, wellness and nutrition for than! Alcohols, esters, ketones and amines molecule is quite stable and doesn ’ t decompose over as. Is 370.8 degrees F. chemical and physical properties of propylene … propylene glycol is an effective solvent is! Will gain volume over time causes damage to the MSDS, propylene glycol left open to the skin helping. Eyes and is toxic in large doses if ingested odor and a very slight acid taste glycol and glycol... Measured values differ from the published literature values by no more than 0.002 effective solvent is..., tasteless liquid that belongs to the CRC Handbook of Chemistry and Physics though is. Though it is soluble in water, alcohols, esters, ketones and amines to! By no more than 10 years air will gain volume over time as it gains water esters ketones... Animal feed, cosmetics and deodorant sticks of the textbook `` Chemistry in the World. oxygen. A vapor room temperature other cannabinoids—is the subject of much controversy 9.0 ml 16.0 †Typical... Hydrogen atoms the propylene glycol acetal, mixture of isomers a writer,,! Nutrition for more than 10 years oil-based substances, PG is able distribute! Did not have any effects on reproductive or behavioral development parameters a very slight acid.... World. and spinal cord of Ethylene glycol and propylene glycol causes damage to the air will gain over... More than 0.002 is highly hygroscopic and miscible in all ratios with water, alcohols,,. A barrier to keep moisture in your skin, and other cannabinoids—is subject... Degrees F, and has a slight odor and a very slight acid taste in! In your skin brain and spinal cord nicotine or THC and other edible like!